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FPRE080 provides a solution for RNA secondary‑structure prediction. Through minimal free‑energy modeling enhanced by parameter pruning and stochastic beam search, it delivers state‑of‑the‑art performance on a rigorously curated benchmark (Dataset 015958) while requiring modest computational resources. The open‑source implementation (GitHub: mina-kitano/fpre080 ) invites community adoption and further development. fpre080 mina kitano015958 min free
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