Open Systems Pharmacology

Y The Last Man Episode 1

Reliable, powerful and easy-to-use modeling & simulation tools for pharmaceutical and other life-sciences applications. Qualified and accepted by the scientific community including academia, regulatory agencies and industry. Available free to everyone.

Essentials

Download OSP Suite

Explore the full functionality of the OSP suite. PBPK, PBPK/PD, QSP – the OSP Suite gives you the flexibility to build it all without having to start from scratch.

Forum

Have your questions answered or provide answers to others. The Forum is a great way to stay up-to-date on the community buzz around OSP.

Documentation

Need to find out how to use a feature? Looking to understand the inner workings of the model? Here you’ll find the extensive OSP manual and qualification documents.

News & Release

Save the Date: OSP Community Conference 2026

In Beerse, Antwerp September 24th and 25th

Open Systems Pharmacology Suite - Version 12 Update 2

We are pleased to announce the new release of the OSP Suite Version 12 Update 2 which is now available for download.

WORKSHOP AT ACOP COLORADO.

Join ESQlabs at the ACoP Conference in Colorado Building Scalable PBPK-QSP Models - Modularization in MoBi for OSP Suite V12.

Ready to take the plunge? Download

Note: This draft is based on the 2021 FX on Hulu television adaptation, which expands significantly on the source material by Brian K. Vaughan and Pia Guerra.

If you are looking for a show that blends political thriller elements with high-stakes survival drama, Y: The Last Man Episode 1 is an essential watch. Share public link

The episode splits its focus among several key figures across different social and political strata:

Unlike the comics, which begin after the mass death, the show spends most of the pilot introducing the cast in their normal lives.

Unlike many post-apocalyptic stories that drop viewers directly into the ruined aftermath, "Unmanned" spends the majority of its runtime in the ordinary world. The narrative builds a sense of dread by showing the mundane, everyday lives of its characters right before the rug is pulled out from under them.

In Brooklyn, Yorick’s sister is attending an AA meeting to fulfill a DUI requirement. She is a cynical and emotionally closed-off EMT who is secretly having an affair with her married partner, Mike. Hero provides the gritty, street-level perspective.

Publications & Models

Models

Glucose Insulin Model

Scientifically exciting for diabetes researchers. Technically exciting for everyone with PBPK models of glucose, insulin, and glucagon coupled through non-mechanistic PD as well as systems pharmacology PD models.

Publications

Journal Publications

Growing list of scientific journal publications that relates to OSP or describes work with PK-Sim® or MoBi®. Add your own contributions and label them or others appropriately to further grow and structure this database.

Take a look at all our models Browse

Y The Last Man Episode 1

Note: This draft is based on the 2021 FX on Hulu television adaptation, which expands significantly on the source material by Brian K. Vaughan and Pia Guerra.

If you are looking for a show that blends political thriller elements with high-stakes survival drama, Y: The Last Man Episode 1 is an essential watch. Share public link Y The Last Man Episode 1

The episode splits its focus among several key figures across different social and political strata: Note: This draft is based on the 2021

Unlike the comics, which begin after the mass death, the show spends most of the pilot introducing the cast in their normal lives. Share public link The episode splits its focus

Unlike many post-apocalyptic stories that drop viewers directly into the ruined aftermath, "Unmanned" spends the majority of its runtime in the ordinary world. The narrative builds a sense of dread by showing the mundane, everyday lives of its characters right before the rug is pulled out from under them.

In Brooklyn, Yorick’s sister is attending an AA meeting to fulfill a DUI requirement. She is a cynical and emotionally closed-off EMT who is secretly having an affair with her married partner, Mike. Hero provides the gritty, street-level perspective.

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