To understand how the high-stakes narrative evolved, it helps to examine how the story shifted focus across each individual season. Year Aired Primary Location Core Objective 2005–2006 Fox River State Penitentiary Breaking Lincoln Burrows out of death row. Season 2 2006–2007 Cross-country (On the run) Evading the FBI and finding hidden millions. Season 3 2007–2008 Sona Federal Penitentiary (Panama) Breaking out of a lawless, riot-run prison. Season 4 2008–2009 Los Angeles / Miami Dismantling the corrupt government syndicate "The Company". Season 5 Ogygia Prison (Yemen) Resurrecting Michael Scofield and escaping a war zone. Season 1: The Blueprint of Fox River
